Kong, Xinyi; Xiao, Kang; Wang, Kewei; LI, Wenwen; Sun, Jing; Wang, Zhongyang

OPTICS LETTERS

2023, 48, 1539-4794

Kong, Xinyi; Xiao, Kang; Wang, Kewei; LI, Wenwen; Sun, Jing; Wang, Zhongyang

In this Letter, we present a new, to the best of our knowl-edge, form of single-exposure quantitative phase microscopy based on the phase retrieval method by recording the band-limited image and its Fourier image simultaneously. Applying the intrinsic physical constraints of microscopy systems in the phase retrieval algorithm, we remove the inherent ambiguities of the reconstruction and achieve a rapid iterative convergence. In particular, this system does not require tight support of the object and the oversampling needed in coherent diffraction imaging. We have demon-strated that, in both simulations and experiments, the phase can be rapidly retrieved from a single-exposure measure-ment using our algorithm. The presented phase microscopy provides a promising technique for real-time quantitative biological imaging. & COPY; 2023 Optica Publishing Group