2003年毕业于德国马尔堡大学生物系分子遗传专业，论文研究古细菌氢酶的遗传调控机制；2004-2010年在美国多所大学开展微生物的遗传机制、氢酶的表达及生化性能研究；2011年起在中国科学院上海高等研究院从事低碳生物转化、生物医药中间体的合成生物学研究，同时也进行氢酶在体外生物转化中的基础及应用研究。

1. 生物医药产品的微生物合成
2. 酶工程及应用
3. 氢酶表达及体外生物转化

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1. 科技部国家重点研发项目, "糖水氢是系统-体外多酶高效产氢及氢电装置的基础及工程研究"，课题1负责人，2022-2027
2. 国家自然科学基金面上项目, “产胞外多糖大肠杆菌S17-3高密度生长的分子机理及2''-岩藻糖基乳糖的合成应用研究"，项目负责人，2021-
     2024
3. 上海市科委国际合作项目“极端腈水解酶生物降解系统的构建及其污染物处理应用研究”，项目负责人，2021-2024.

1.Sánchez-SanMartín J, Márquez SL, Espina G, Cortés-Antiquera R, Sun J, Blamey JM. Evaluation of Antibiotic Biodegradation by a Versatile ａｎｄ Highly Active Recombinant Laccase from the Thermoalkaliphilic Bacterium?Bacillus?sp. FNT. Biomolecules. 2024 Mar 19;14(3):369. doi: 10.3390/biom14030369. PMID: 38540787; PMCID: PMC10968384.
2.Zhang S, Liu M, Liu Y, Yuan D, Sun J, A native phosphoribosyltransferase, PncB, is the key NMN synthase ｉｎ Bacillus subtilis, Process Biochemistry, 139, April 2024, 137-145, doi.org/10.1016/j.procbio.2024.02.004.
3.Xie Y, Wu X, Fu C, Duan H, Shi J, Blamey JM, Sun J. Rational Design of an α-1,3-Fucosyltransferase for the Biosynthesis of 3-Fucosyllactose ｉｎ?Bacillus subtilis?ATCC 6051a via?De Novo?GDP-l-Fucose Pathway. J Agric Food Chem. 2024 Jan 6. doi: 10.1021/acs.jafc.3c07604.?
4.Fu C, Xu X, Xie Y, Liu Y, Liu M, Chen A, Blamey JM, Shi J, Zhao S, Sun J. Rational design of GDP?D?mannose mannosyl hydrolase for microbial L?fucose production. Microb Cell Fact. 2023 Mar 24;22(1):56. doi: 10.1186/s12934-023-02060-y. PMID: 36964553; PMCID: PMC10037897.
5.Liu X, He B, Zhang J, Yuan C, Han S, Du G, Shi J, Sun J, Zhang B. Phytosterol conversion into C9 non-hydroxylated derivatives through gene regulation ｉｎ Mycobacterium fortuitum. Appl Microbiol Biotechnol. 2023 Dec;107(24):7635-7646. doi: 10.1007/s00253-023-12812-w. Epub 2023 Oct 13.
6.Yuan C, Li Y, Han S, He B, Zhai X, Lin W, Shi J, Sun J, Zhang B. Functional analysis of acyl-CoA dehydrogenases ａｎｄ their application to C22 steroid production. Appl Microbiol Biotechnol. 2023 Jun;107(11):3419-3428. doi: 10.1007/s00253-023-12541-0. Epub 2023 Apr 24. PMID: 37093308.
7.Chenyang Yuan, Zhiguo Ma, Yixin Li, Jingxian Zhang, Xiangcen Liu, Suwan Han, Guilin Du, Jiping Shi, JunSong Sun,ａｎｄ Baoguo Zhang, Production of 21-hydroxy-20- methyl-pregna-1,4-dien-3-one by modifying multiple genes ｉｎ Mycolicibacterium, Appl Microbiol Biotechnol, 2023 Feb 2, doi: 10.1007/s00253-023-12399-2.