郁峰，研究员，研究方向为结构生物学和蛋白晶体学实验方法研究。完成了一系列的天然产物合成途径中关键酶和核酸相关蛋白的结构解析和功能研究。近年来致力于发展基于晶体学片段筛选的药物发现技术。

1. 蛋白质晶体学实验方法和应用
2. 基于片段的药物发现
3. 结构生物学

1 国家重点研发计划, 临床严重耐药致病菌通用疫苗研发, 2021-12 至 2024-11, 子课题负责人
2.国家自然科学基金面上项目, 弧菌属群体感应关键蛋白VqmA的结构、机制、特异性小分子药物设计及噬菌体治疗研究, 2020-01-01 至 2023-12-31, 项目负责人

1. The crystal structures of Sau3AI with ａｎｄ without bound DNA suggest a self-activation-based DNA cleavage mechanism, Structure, Structure 31, 1463–1472
2. Finback: a web-based data collection system at SSRF biological macromolecular crystallography beamlines, Journal of Synchrotron Radiation, 2024, 31, 378–384
3. BL02U1: the relocated macromolecular crystallography beamline at the Shanghai Synchrotron Radiation Facility, Nuclear Science ａｎｄ Techniques, 2023, 34:193
4. Complex Crystal Structure Determination of Hsp90(N)-NVP-AUY922 ａｎｄ Ｉｎ Vitro Anti-NSCLC Activity of NVP-AUY922, Frontiers ｉｎ Oncology, 2022, Article 847556
5. Deploying the Big Data Science Center at the Shanghai Synchrotron Radiation Facility: the first superfacility platform ｉｎ China, Machine Learning: Science ａｎｄ Technology 2 (2021) 035003
6. Anti-NSCLC activity ｉｎ vitro of Hsp90N inhibitor KW-2478 ａｎｄ complex crystal structure determination of Hsp90N-KW-2478, Journal of Structural Biology 213 (2021) 107710
7. Crystal structure details of Vibrio fischeri DarR ａｎｄ mutant DarR-M202I from LTTR family reveals their activation mechanism, International Journal of Biological Macromolecules 183 (2021) 2354–2363
8. Aquarium: an automatic data-processing ａｎｄ experiment information management system for biological macromolecular crystallography beamlines, Journal Of Applied Crystallography (2019). 52, 472–477
9. Crystal structure of the Vibrio cholerae VqmA-ligand-DNA complex provides insight into ligand-binding mechanisms relevant for drug design, Journal Of Biological Chemistry (2019) 294(8) 2580–2592
10. Crystal structures of phage NrS-1 N300-dNTPs-Mg2+ complex provide molecular mechanisms for substrate specificity, Biochemical ａｎｄ Biophysical Research Communications 515 (2019) 551e557