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孙波

      姓名             孙波
      性别             男
      职称             正高级工程师四级
      电子邮件       sunb@sari.ac.cn
      通讯地址        上海市浦东新区张衡路239号
      个人网页       https://teacher.ucas.ac.cn/~bo.sun








招生专业

材料与化工;信息与通信工程;生物与医药;

简历

孙波,男,正高级工程师,中国科学院上海高等研究院上海光源中心BL14B衍射线站运行负责人。

研究方向

1、同步辐射衍射实验方法学
2、同步辐射实验技术应用

获奖及荣誉

承担科研项目情况

1、国家自然科学基金面上项目,基于串行样品传输的劳厄晶体学实验方法与蛋白质晶体结构实例研究,项目负责人,2023.1-2026.12
2、国家自然科学基金国家重大科研仪器研制项目,多因素环境下材料微结构/应力同步辐射原位微衍射(SR-μXRD)系统,参与,2020.1-2024.12
3、广东省基础与应用基础研究重大项目,基于同步光源和散裂中子源的劳厄衍射方法及应用,参与,2023.12-2028.12

代表论著

1、文章
[1] W. Liu, K. Zhang, Y. Zhang, J. He, B. Sun. Utilization of merge sorting method to improve the stitching efficiency on multi-scene image stitching. Applied Sciences. 13:2791. (2023)
[2] L. Wang, Y. Zhang, Y. Lin, S. Yan, Y. Xu, B. Sun, Ship detection algorithm based on YOLOv5 network improved with lightweight convolution and attention mechanism. Algorithms. (2023) 16(12):534
[3] M. Xu, D. Xu, M. Gao, X. Zhuang, W. Wang, B. Sun, T. Ran. Structural basis for substrate binding and catalytic mechanism of the key enzyme VioD in the violacein synthesis pathway. Proteins. 91(7):956-966 (2023)
[4] M. Xu, Q. Xu, M. Wang, S. Qiu, D. Xu, W. Zhang, W. Wang, J. He, Q. Wang, T. Ran, B. Sun. Crystal structures of TTHA1265 and TT9HA1264/TTHA1265 complex reveal an intrinsic heterodimeric assembly. International Journal of Biological Macromolecules. 207:424–433 (2022)
[5] Q. Xiao, M. Xu, W. Wang, T. Wu, W. Zhang, W. Qin, B. Sun. Utilization of AlphaFold2 to predict MFS protein conformations after selective mutation. International Journal of Molecular Sciences. 23: 7235 (2022)
[6] Q. Xu, N. Sun, Q. Xiao, C. Huang, M. Xu, W. Zhang, L. Li, Q. Wang, V. Olieric, W. Wang, J. He, B. Sun. The crystal structure of MreC provides insights into polymer formation. FEBS Open Bio. 12:340–348 (2022)
[7] S. Qiu, D. Xu, M. Xu, H. Zhou, N. Sun, L. Zhang, M. Zhao, J. He, T. Ran, B. Sun, W. Wang. Crystal structures of PigF, an O-methyltransferase involved in the prodigiosin synthetic pathway, reveal an induced-fit substrate-recognition mechanism. IUCrJ. 9:316–327 (2022)
[8] W. Zhao, W. Wen, K. Liu, Y. Zhang, Q. Wang, G. Yin, B. Sun, Y. Zhang, X. Gao. An improved point cloud upsampling algorithm for X-ray diffraction on thermal coatings of aeroengine blades. Applied Sciences. 12:6807. (2022)
[9] Y. Zhang, W. Zhao, B. Sun, Y. Zhang, W. Wen. Point cloud upsampling algorithm: a systematic review. Algorithms. 15(4):124 (2022)
[10] Y. Han, Q. Zhuang, B. Sun, W. Lv, S. Wang, Q. Xiao, B. Pang, Y. Zhou, F. Wang, P. Chi, Q. Wang, Z. Li, L. Zhu, F. Li, D. D, Y. Chiang, Z. Li, R. Ren. Crystal structure of steroid reductase SRD5A reveals conserved steroid reduction mechanism. Nature Communications.  12(1):449 (2021)
[11] J. Qin, Y. Zhang, H. Zhou, F. Yu, B. Sun, Q. Wang. Protein Crystal Instance Segmentation Based on Mask R-CNN. Crystals. 11:157 (2021)
[12] C. Wang, Q. Xiao, H. Duan, J. Li, J. Zhang, Q. Wang, L. Guo, J. Hu2, B. Sun, D. Deng. Molecular basis for substrate recognition by the bacterial nucleoside transporter NupG. Journal of Biological Chemistry. 296:100479 (2021)
[13] C. Wu, J. Xian, Y. Wang, Q. Xiao, L. Ma, Y. Li, H. Chen, Q. Lei, Q. Zhang, B. Sun, Y. Wang. The high-resolution X-ray structure of vinca-domain inhibitors of microtubules provides a rational approach for drug design. FEBS Letters. 595:195–205 (2021)
[14] F. Zhao, B. Sun, L. Yu, Q. Xiao, Z. Wang, L. Chen, H. Liang, Q. Wang, J. H, D, Yin. A novel sample delivery system based on circular motion for in situ serial synchrotron crystallography. Lab on a Chip. 20:3888-3898 (2020)
[15] T. Ran, W. Li, B. Sun, M. Xu, S. Qiu, D. Xu, J. He, W. Wang. Crystal structure of mature myroilysin and implication for its activation mechanism. International Journal of Biological Macromolecules. 156:1556-1564 (2020)
2、专利
[1] 一种盘式蛋白质结晶板的驱动装置, 发明专利, 2022, 专利号: CN111100182B
[2] 一种同步辐射串行晶体学静电纺丝上样装置以及一种基于同步辐射的串行晶体学实验方法, 发明专利, 2020, 专利号: CN111678929A
[3] 一种用于自动上样机械手测试的杜瓦结构, 发明专利, 2020, 专利号: CN111103314A
[4] 膜蛋白自动化脂立方相结晶系统, 实用新型专利, 2016, 专利号: CN205368542U
3、软件著作权
[1] 超高温激光热源温度自反馈控制软件(Lightsaber1.0), 2023, 登记号: 2024SR0115008